Patients are unwilling to enter clinical trials

How Drugs are Evaluated: Patients’ Guide to Randomized Clinical Trials

Following positive epidemiologic studies, statins to enter clinical trials for cancer prevention.

1172 NEWS Journal of the National Cancer Institute, Vol. 97, No. 16, August 17, 2005 Statins grabbed the headlines earlier this year when several epidemiologic studies produced promising results that the cholesterol-lowering drugs might be associated with reduced risks of several cancers, including breast, colorectal, lung, and prostate cancers. Although some researchers have called for large r...

Evaluation of Clinical Trials

In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...

Evidence Based Medicine: Clinical Trials

Evidence based medicine is very important for success of modern medicine. It is the ongoing process of using the most reliable evidence from clinical studies, scientific understanding and medical practice to make the best possible medical choice for patients. Evidence based medicine is how medicine advances and how we get improvements in life expectancy and quality of life. It not only identifi...

Clinical trials are bureaucratic, opaque, and offputting to researchers and patients, MPs hear.

Clinical trials are still too bureaucratic, not transparent enough, and offputting to potential researchers as well as participants, MPs have been told. The clinical trials system and governing regulations in the United Kingdom must be improved, expert witnesses told the House of Commons Science and Technology Committee at an evidence session held on 13 March. The committee is holding an inquir...